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Related Experiment Videos

Can RDoC Help Find Order in Thought Disorder?

Alex S Cohen1, Thanh P Le1, Taylor L Fedechko1

  • 1Department of Psychology, Louisiana State University, Baton Rouge, LA, USA.

Schizophrenia Bulletin
|April 12, 2017
PubMed
Summary

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The Research Domain Criteria (RDoC) framework offers a new approach to understanding thought disorder in serious mental illnesses. This framework can improve assessments and treatments for these complex conditions.

Area of Science:

  • Neuroscience and Psychiatry
  • Cognitive Science
  • Computational Linguistics

Background:

  • Thought disorder is a complex symptom in serious mental illnesses (SMIs) with limited understanding and ineffective treatments.
  • Current clinical assessments of thought disorder are restricted to extreme behaviors.
  • Decades of research have not significantly improved our understanding or treatment of thought disorder.

Purpose of the Study:

  • To propose the Research Domain Criteria (RDoC) framework as a novel approach to studying thought disorder.
  • To outline methods for operationalizing and quantifying thought disorder within the RDoC framework.
  • To highlight the potential of RDoC for developing improved assessments and treatments for thought disorder.

Main Methods:

  • Applying the RDoC framework to conceptualize thought disorder.
Keywords:
computational psychiatrydisorganizationlanguagepsycholinguisticsschizophreniaserious mental illness

Related Experiment Videos

  • Utilizing psycholinguistic sciences to operationalize language constructs within RDoC.
  • Employing technologically advanced paradigms for naturalistic behavioral sampling.
  • Using computational modeling to analyze interconnected linguistic, cognitive, affective, and social functions.

    • Main Results:

    • The RDoC framework provides a structured approach to dissecting the phenotype and mechanisms of thought disorder.
    • Integrating psycholinguistics, advanced technology, and computational modeling can objectify and quantify thought disorder.
    • Thought disorder likely involves network dysfunctions across multiple RDoC constructs, not a single isolated issue.

    Conclusions:

    • The RDoC framework is a valuable tool for integrating multidisciplinary research on thought disorder.
    • Operationalizing thought disorder within RDoC can lead to more precise assessments and targeted interventions.
    • Future research should focus on the dynamic and network-based nature of thought disorder within the RDoC framework.