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Systems chemistry.

Gonen Ashkenasy1, Thomas M Hermans, Sijbren Otto

  • 1Department of Chemistry, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Chemical Society Reviews
|April 19, 2017
PubMed
Summary
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Systems Chemistry pioneers complex molecular systems with emergent properties beyond individual components. This field explores self-assembly, molecular motion, and networks, aiming for life

Area of Science:

  • Chemical Sciences
  • Systems Chemistry

Background:

  • The chemical sciences are advancing into Systems Chemistry, focusing on designing molecules and understanding their interactions.
  • Systems Chemistry aims to create complex molecular systems exhibiting emergent properties.

Purpose of the Study:

  • To provide an overview of the current state-of-the-art in Systems Chemistry.
  • To highlight recent advancements and discuss future challenges and prospects in the field.

Main Methods:

  • Review of recent highlights in Systems Chemistry.
  • Discussion of challenges in designing complex chemical systems.
  • Exploration of future prospects, including de novo synthesis of life.

Main Results:

  • Showcases diverse highlights: out-of-equilibrium self-assembly, chemically fuelled molecular motion, compartmentalised chemical networks, and designed oscillators.

Related Experiment Videos

  • Identifies key challenges: formation-destruction systems, maintaining non-equilibrium states, feedback loops, and replication chemistry.
  • Discusses prospects: de novo synthesis of life, self-synthesising and self-repairing chemical factories.

    • Conclusions:

    • Systems Chemistry is a rapidly developing field with significant potential.
    • The field is poised to address grand challenges in chemistry, potentially leading to artificial life and advanced chemical factories.