Related Experiment Video
Updated: Jul 24, 2026

In Vivo Immunogenicity Screening of Tumor-Derived Extracellular Vesicles by Flow Cytometry of Splenic T Cells
Published on: September 23, 2021
Mobilizing Immune Cells With Exercise for Cancer Immunotherapy
Richard J Simpson1, Austin B Bigley, Nadia Agha
11Laboratory of Integrated Physiology, Department of Health and Human Performance, University of Houston; 2Department of Behavioral Sciences, University of Texas MD Anderson Cancer Center, Houston, TX; and 3Program for Cell Enhancement and Technologies for Immunotherapy, Children's National Health System and The George Washington University, Washington, DC.
Abstract:
Hematopoietic stem cell (HSC) transplantation and adoptive transfer immunotherapy are effective in treating blood cancers and posttransplant infections, but low-circulating cell numbers in patients and donors are oftentimes a limiting factor. We postulate that a single exercise bout will increase the yield of patient- and donor-derived HSCs and cytotoxic lymphocytes to improve this form of treatment for cancer patients.
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