Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Vaccinations

Vaccinations

Immunological Memory

Immunological Memory

Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.

Chickenpox

Chickenpox

Chickenpox is an acute, highly contagious disease caused by the varicella-zoster virus (VZV), a double-stranded DNA virus belonging to the Herpesviridae family. Its transmission occurs primarily through the inhalation of respiratory droplets or direct contact with vesicular fluid from skin lesions. The incubation period typically ranges from 10 to 21 days, during which the virus replicates and disseminates through sequential phases within the host. Although generally self-limiting in children,...

Poliomyelitis

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...

Rabies

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Growth hormone treatment adjusted for growth hormone sensitivity in idiopathic short stature.

European journal of endocrinology·2025

Same author

The simplified oral flucloxacillin absorption test: an accurate method to identify patients with inadequate oral flucloxacillin absorption.

The Netherlands journal of medicine·2019

Same author

Rifampin levels in daily practice: the accuracy of a single measurement.

The Netherlands journal of medicine·2018

Same author

[Diabetes, not harmless in young adults].

Nederlands tijdschrift voor geneeskunde·2017

Same author

[Fosfomycin, an old antibiotic with new possibilities].

Nederlands tijdschrift voor geneeskunde·2017

Same author

Disease burden of congenital cytomegalovirus infection at school entry age: study design, participation rate and birth prevalence.

Epidemiology and infection·2015

Search research articles

Related Experiment Video

Updated: Jul 23, 2026

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

Published on: September 19, 2016

[Measles after MMR-vaccination].

R van Grootveld¹, L M Klitsie, D C M van der Kaay

¹Leids Universitair Medisch Centrum, afd. Medische Microbiologie, Leiden.

Nederlands Tijdschrift Voor Geneeskunde

|April 20, 2017

Summary

Mild symptoms like rash after the measles, mumps, and rubella (MMR) vaccine are common and mimic wild measles. Reassurance, not extensive testing, is often best for parents concerned about post-vaccination reactions.

More Related Videos

Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis

Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis

Published on: May 12, 2023

Detection of Rabies IgG and IgM Antibodies Using the Rabies Indirect Fluorescent Antibody Test

Detection of Rabies IgG and IgM Antibodies Using the Rabies Indirect Fluorescent Antibody Test

Published on: January 19, 2024

Related Experiment Videos

Last Updated: Jul 23, 2026

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

Published on: September 19, 2016

Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis

Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis

Published on: May 12, 2023

Detection of Rabies IgG and IgM Antibodies Using the Rabies Indirect Fluorescent Antibody Test

Detection of Rabies IgG and IgM Antibodies Using the Rabies Indirect Fluorescent Antibody Test

Published on: January 19, 2024

Area of Science:

Pediatrics
Immunology
Public Health

Background:

The Dutch national vaccination program includes the measles, mumps, and rubella (MMR) vaccine for all children.
Live attenuated viruses in the MMR vaccine replicate minimally post-administration.
This replication can cause mild, transient symptoms like fever, rash, and conjunctivitis, typically 5-14 days after vaccination.

Observation:

A 14-month-old boy presented with a significant rash 13 days post-MMR vaccination.
Diagnostic tests confirmed measles, leading to parental vaccine hesitancy.
The timing of symptoms raised questions about vaccine reaction versus wild-type infection.

Findings:

Post-MMR vaccination symptoms can closely resemble wild-type measles infection.
The low incidence of wild-type measles suggests vaccination reaction is a likely cause.
Symptoms typically manifest within 14 days of receiving the MMR vaccine.

Implications:

Distinguishing vaccine-induced symptoms from wild-type infections is crucial for public health.
Extensive diagnostic procedures can cause parental distress and vaccine hesitancy.
Healthcare providers should prioritize parental reassurance regarding expected post-vaccination responses.