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Viral Recombination

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.

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Updated: Mar 3, 2026

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Published on: March 13, 2018

Chikungunya Virus.

David M Vu¹, Donald Jungkind², Angelle Desiree LaBeaud¹

¹Department of Pediatrics, Stanford University School of Medicine, 300 Pasteur Drive, G312, Stanford, CA 94305, USA.

Clinics in Laboratory Medicine

|May 2, 2017

Summary

This summary is machine-generated.

Chikungunya virus (CHIKV) causes long-term joint pain, impacting economies globally. Further research into CHIKV pathogenesis is crucial for effective prevention and control strategies.

Keywords:

Alphavirus Arbovirus Chikungunya virus Togaviridae

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Area of Science:

Virology
Epidemiology
Public Health

Background:

Chikungunya virus (CHIKV) infection is associated with prolonged, debilitating arthralgia.
The full spectrum of long-term health consequences of CHIKV infection remains poorly understood.
The economic and societal impact of CHIKV-related illness requires further evaluation.

Purpose of the Study:

To highlight the need for a comprehensive understanding of CHIKV pathogenesis.
To emphasize the importance of addressing the long-term sequelae of chikungunya infection.
To underscore the necessity of developing effective prevention and control measures for CHIKV.

Main Methods:

This study is a review and synthesis of current knowledge on chikungunya virus.
It analyzes the impact of prolonged arthralgia on global economies.
It identifies gaps in understanding CHIKV pathogenesis and disease control.

Main Results:

Long-term arthralgia is a significant, yet ill-defined, sequela of CHIKV infection.
The economic burden of chikungunya is substantial due to prolonged illness.
Significant knowledge gaps exist regarding CHIKV pathogenesis and long-term effects.

Conclusions:

A deeper understanding of CHIKV pathogenesis is a priority for public health.
Effective strategies for CHIKV prevention and control depend on better knowledge of the virus and its effects.
Addressing the long-term health and economic impacts of chikungunya is essential.