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Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid
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Microneedling therapy with and without platelet-rich plasma
Peter W Hashim1, Zachary Levy1, Joel L Cohen2
1Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Cutis
|May 12, 2017
Summary
Microneedling with platelet-rich plasma (PRP) enhances cosmetic results for dermatologic conditions. This combination therapy appears effective and safe, improving outcomes without increased adverse events.
Area of Science:
- Dermatology
- Regenerative Medicine
Background:
- Microneedling is a popular dermatologic treatment.
- Platelet-rich plasma (PRP) is explored as an adjunct therapy.
Purpose of the Study:
- To review evidence comparing microneedling with and without PRP.
- To assess PRP's impact on microneedling outcomes and safety.
Main Methods:
- Literature review of studies comparing microneedling alone versus microneedling with PRP.
- Analysis of cosmetic outcomes and adverse events.
Main Results:
- Preliminary literature suggests PRP enhances microneedling cosmetic outcomes.
- No increased risk of adverse events was observed with PRP adjunct therapy.
Conclusions:
- PRP may augment the cosmetic benefits of microneedling.
- Combining microneedling with PRP appears safe for dermatologic treatments.

