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Keyboard: A Novel Bayesian Toxicity Probability Interval Design for Phase I Clinical Trials

Fangrong Yan1, Sumithra J Mandrekar2, Ying Yuan3

  • 1Division of Biostatistics, China Pharmaceutical University, Nanjing, China.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|May 27, 2017
PubMed
Summary

The keyboard design is a novel Bayesian approach for phase I oncology trials, improving the identification of the maximum tolerated dose (MTD) compared to traditional methods. It offers enhanced safety and precision in dose escalation studies.

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