[MODIFIED SYSTEM OF THROMBOPROPHYLAXIS IN PATIENTS WITH SURGICAL PROFILE]

The aim of the study was to reduce the incidence of postoperative thrombosis in the veins of the inferior vena cava basin under planned surgical interventions by using a modified thromboprophylaxis method. Two groups of patients were studied in a total of 698 patients who underwent a risk assessment of postoperative venous thromboembolism (PVTE) using the J. Caprini scale (2012). According to the patients indicated in determining the degree of risk of HTHP development according to the J. Caprini scale, the level of surgical stress was simultaneously determined. The level of the latter was established by the content of glucose and cortisol in the blood in the preoperative period, during the traumatic stage of surgical intervention and in the early postoperative period. Introduction to the J. Caprini system of the degree of surgical stress objectifies the system for determining the risk of postoperative venous thrombosis. Inclusion of UFH (the prevailing influence on factor II) in the system of thromboprophylaxis of LMWH (predominant influence on Xa factor) with planned surgical interventions made it possible to reduce the incidence of postoperative thrombosis of the veins in the NIP basin by 1.8 (p<0.001) times.