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Updated: Feb 26, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
Published on: May 22, 2019
FACTORS ASSOCIATED WITH POST-STROKE FATIGUE WITHIN THE FIRST 3 MONTH AFTER STROKE
I Delva1, N Lytvynenko1, M Delva1
1Ukrainian Medical Stomatological Academy, Poltava, Ukraine.
Abstract:
Aim - identify socio-demographic, personal and psychological factors associated with certain post-stroke fatigue (PSF) domains within first 3 months after stroke. There were examined patients consequently in definite time points after ischemic or hemorrhagic strokes: at hospital stay (234 patients), in 1 month (203 patients) and in 3 months (176 patients). Global PSF and certain PSF domains were measured by multidimensional fatigue inventory-20 (MFI-20) scale. In multivariate logistic regression analysis the majority of variables (gender, marital status, education level, smoking status, level of alcohol consumption, apathetic impairments, arterial hypertension, atrial fibrillation, ischemic heart disease, diabetes mellitus, body mass index, waist circumference) were not significantly associated with any PSF domain risk at any time point after stroke. On the other hand, it had been found reliable associations between risk of global PSF and employing status before stroke, pre-stroke fatigue, anxiety symptoms, excessive daytime sleepiness, pain. Majority of risk factors for specific PSF domains (physical, mental, activity-related, motivational) are the same as for global PSF. The exception is mild cognitive impairments for mental PSF and depression signs for motivational PSF. Management of modifiable risk factors (anxiety and depression signs, excessive daytime sleepiness, chronic pain) probably may be helpful for PSF prevention within first 3 months after stroke.
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