[PATHOMORPHOLOGICAL CHANGES UNDER LATENT MASTOIDITIS]

Kh Chitadze1, T Jorbenadze1, M Adamia1

  • 11Ivane Javakhishvili Tbilisi State University; 2S. Khechinashvuili University Clinic, Ybilisi, Georgia.

Georgian Medical News
|July 21, 2017
PubMed

Insights

Latent mastoiditis involves inflammatory and destructive changes in middle ear tissues. Complete surgical removal of affected tissue and bone is crucial to prevent relapse and reduce disability.

Area of Science:

  • Otolaryngology
  • Pathology
  • Surgical Anatomy

Background:

  • Latent mastoiditis is often undertreated due to insufficient understanding of its pathological distribution.
  • Morphological changes in middle ear soft and bone tissues are key to diagnosis.

Purpose of the Study:

  • To investigate structural changes in middle ear tissues in latent mastoiditis.
  • To correlate histological findings with treatment strategies for latent mastoiditis.

Main Methods:

  • Histological examination of soft and bone tissues from the middle ear.
  • Tissue fixation, processing, decalcification (15-20% nitric acid), and staining (hematoxylin and eosin).
  • Microscopic analysis of tissue sections using a rotating microtome.

Main Results:

  • Microscopic findings revealed inflammatory-destructive changes in mucous and bone tissues.
  • Observed serous and fibrin inflammation with significant edema.
  • Inflammatory infiltration included lymphocytes, macrophages, plasmocytes, and leukocytes; bone tissue showed osteitis and osteomyelitis indicators.

Conclusions:

  • Histological evidence supports osteitis and osteomyelitis in latent mastoiditis.
  • Surgical intervention with complete sanitization of affected tissue and bone is recommended.
  • Effective treatment can reduce mortality and disability rates associated with latent mastoiditis.

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