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Endaural Endoscopic Atticoantrotomy Retrograde Mastoidectomy using a Constant Suction Bone-drilling Technique
Published on: May 23, 2021
[PATHOMORPHOLOGICAL CHANGES UNDER LATENT MASTOIDITIS]
Kh Chitadze1, T Jorbenadze1, M Adamia1
11Ivane Javakhishvili Tbilisi State University; 2S. Khechinashvuili University Clinic, Ybilisi, Georgia.
Abstract:
In our opinion it is caused by incomplete awareness of the distribution of pathological process and the character of morphological changes in the patients. In this regard, we studied structural changes in the soft and bone tissue taken from various cavities of the middle ear system. Operating material was formed in paraffin after the fixation and proper processing. We proceed with decalcification of bone tissues in 15-20% nitric acid. We painted 5-6 mm thick peels prepared on the rotating microtome with hematoxylin and eosin. The microscopic examination revealed inflammatory-destructive changes in the mucous membrane as well as in the bone tissues, also serous inflammation-fibrin inflammation, and well-expressed edema. The inflammatory infiltration demonstrated the presence of lymphocytes, macrophages, plasmocytes and also predominantly dislocated leukocytes. There were also revealed various amount of glandular structures. The bone tissues - along with the inflammatory infiltration - revealed destructive cells, which contained osteoclast, epithelial cells and fibroblasts. The mentioned structural changes should be assessed as demonstration of an osteitis and osteomyelitis. Based on the above mentioned, we believe that treatment of latent mastoiditis requires surgical method and it is necessary the complete sanitization of not only the granulating tissue but the damaged bone masses. Otherwise, the remaining inflammatory nidus may cause a relapse. The correct treatment of latent mastoiditis in turn will reduce the mortality rate and the percentage of disability.
Insights
Latent mastoiditis involves inflammatory and destructive changes in middle ear tissues. Complete surgical removal of affected tissue and bone is crucial to prevent relapse and reduce disability.
Area of Science:
- Otolaryngology
- Pathology
- Surgical Anatomy
Background:
- Latent mastoiditis is often undertreated due to insufficient understanding of its pathological distribution.
- Morphological changes in middle ear soft and bone tissues are key to diagnosis.
Purpose of the Study:
- To investigate structural changes in middle ear tissues in latent mastoiditis.
- To correlate histological findings with treatment strategies for latent mastoiditis.
Main Methods:
- Histological examination of soft and bone tissues from the middle ear.
- Tissue fixation, processing, decalcification (15-20% nitric acid), and staining (hematoxylin and eosin).
- Microscopic analysis of tissue sections using a rotating microtome.
Main Results:
- Microscopic findings revealed inflammatory-destructive changes in mucous and bone tissues.
- Observed serous and fibrin inflammation with significant edema.
- Inflammatory infiltration included lymphocytes, macrophages, plasmocytes, and leukocytes; bone tissue showed osteitis and osteomyelitis indicators.
Conclusions:
- Histological evidence supports osteitis and osteomyelitis in latent mastoiditis.
- Surgical intervention with complete sanitization of affected tissue and bone is recommended.
- Effective treatment can reduce mortality and disability rates associated with latent mastoiditis.
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