Related Experiment Video
Updated: Feb 25, 2026
06:04
Patch Angioplasty in the Rat Aorta or Inferior Vena Cava
Published on: February 27, 2017
11.1K
Late Dacron Patch Inflammatory Reaction after Carotid Endarterectomy
M Alawy1, W Tawfick1, M ElKassaby1
1Western Vascular Institute (WVI), Department of Vascular and Endovascular Surgery, University College Hospital, Galway (UCHG), Newcastle Road, Galway, Ireland.
Summary
Inflammatory reactions to Dacron patches can cause late complications after carotid endarterectomy (CEA). Vein reconstruction is effective, but debridement with muscle coverage may be an option for high-risk patients.
Area of Science:
- Vascular Surgery
- Surgical Complications
- Biomaterials Science
Background:
- Carotid endarterectomy (CEA) is a common procedure to prevent stroke.
- Patch materials used in CEA can be associated with complications.
- Late inflammatory reactions to synthetic patches are a concern.
Purpose of the Study:
- To investigate the incidence and presentation of inflammatory reactions to carotid patches after CEA.
- To differentiate inflammatory reactions from infection as a cause of late complications.
Main Methods:
- A cohort study of patients undergoing elective CEA between 2002 and 2016.
- Utilized computed tomography angiogram, duplex scan, and leucocyte scintigraphy for diagnosis.
- Assessed re-intervention outcomes, histopathology, and cultures.
Main Results:
- Eight patients (1.9%) experienced late Dacron patch inflammatory complications after a mean of 4.1 years.
- Pathology revealed foreign body reaction, with no organisms cultured.
- Re-intervention outcomes varied, with vein reconstruction showing satisfactory results.
Conclusions:
- Late CEA complications may stem from Dacron patch inflammation rather than infection.
- Infection must be ruled out first.
- Vein reconstruction is effective; debridement with muscle coverage is a potential alternative for high-risk patients.
Related Concept Videos
01:26Aneurysm III: Interprofessional Care
387
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
387
01:26Cardiac Catheterization IV: Nursing Management
876
Nursing responsibilities before cardiac catheterization include:Assess for allergies and establish baseline health status.Before cardiac catheterization, assess the patient for allergies to contrast dye. Perform a comprehensive baseline assessment, including vital signs, heart and breath sounds, and a neurovascular assessment of the extremities, noting distal pulses, skin color, and temperature. Instruct the patient to fast for 8-12 hours before the procedure. Evaluate baseline laboratory...
876
01:28Inflammatory Response
17.5K
An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
17.5K