Surface-bound quadruple H-bonded dimers: formation and exchange kinetics
Related Experiment Video
Updated: Feb 25, 2026

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry
Published on: November 29, 2013
Digvijay Gahtory1, Rickdeb Sen, Maarten M J Smulders
1Laboratory of Organic Chemistry, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, The Netherlands. han.zuilhof@wur.nl maarten.smulders@wur.nl.
Abstract:
While the mechanistic details of the dimerization of the self-complementary 2-ureido-4(1H)-pyrimidinone (UPy) motif are well studied in solution, no such investigation is available on a surface. Here we report an extensive study of hydrogen binding kinetics for quadruply H-bonded UPy arrays on aluminum surfaces and explore the ON/OFF capability of such arrays under externally controllable conditions. Also, we investigate the dynamic nature of this system whereby the interfacially H-bonded UPy is displaced by another UPy derivative in solution, and reveal the kinetics of the exchange process.
More Related Videos
07:53Analysis of Complex Molecules and Their Reactions on Surfaces by Means of Cluster-Induced Desorption/Ionization Mass Spectrometry
Published on: March 1, 2020
10:28Probing the Structure and Dynamics of Interfacial Water with Scanning Tunneling Microscopy and Spectroscopy
Published on: May 27, 2018
Related Concept Videos
Hydrogen Bonds
Hydrogen Bonds
Hydrogen Bonds Control the World!
Because hydrogen has very weak electronegativity when it binds with a strongly electronegative atom, such as oxygen or nitrogen, electrons in the bond are unequally shared....
Molecular Orbital Theory II
Radical Formation: Homolysis
Hybridization of Atomic Orbitals II
Stability of Conjugated Dienes
A comparison of the enthalpies of hydrogenation of dienes reveals that conjugated dienes release less heat on hydrogenation, rendering them more stable than their nonconjugated analogs.