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Mesenchymal Stem Cells in Fibrotic Disease

Elie El Agha1, Rafael Kramann2, Rebekka K Schneider3

  • 1Institute of Life Sciences, Wenzhou University, Wenzhou University-Wenzhou Medical University Collaborative Innovation Center of Biomedicine, Wenzhou, Zhejiang, China; Excellence Cluster Cardio-Pulmonary System (ECCPS), Universities of Giessen and Marburg Lung Center (UGMLC), Justus-Liebig-University Giessen, German Center for Lung Research (DZL), Giessen, Germany.

Cell Stem Cell
|August 5, 2017
PubMed
Summary

Fibrosis involves abnormal myofibroblast buildup. This review explores how mesenchymal stem cells (MSCs) and MSC-like cells contribute to myofibroblast generation in fibrotic diseases across multiple organs.

Keywords:
lineage tracingmesenchymal stem cellsorgan fibrosis

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