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Updated: Jul 21, 2026

Polygraphic Recording Procedure for Measuring Sleep in Mice
Published on: January 25, 2016
Drug-Induced Hypersomnolence
1Rocky Mountain Sleep Disorders Center, Southern Colorado Family Medicine Residency Program, Department of Family Medicine, University of Colorado School of Medicine, PO Box 3065, Pueblo, CO 81005, USA.
Abstract:
Daytime somnolence is among the most commonly reported drug side effects. The United States has the highest rate of motor vehicular accident (MVA) deaths with sedating drug use a factor in more than 30%. Sedating drug use extends beyond drugs of abuse to sedating medications. This paper presents pharmacodynamics, performance and driving tests, and MVAs for somnolence inducing agents classified as hypnotics, sedatives, and/or sedation as a side effect. This classification, based on the drug tendency to induce next-day sedation after nighttime use, can be cogently used by prescribers, pharmacists, regulatory agencies, and in direct to consumer marketing.
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