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Updated: Feb 24, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Unnatural milieu: Thrombus after transcatheter mitral valve replacement
Jaffar M Khan1, Robert J Lederman1
1Cardiovascular and Pulmonary Branch, Division of Intramural Research, National Heart Lung Institute, National Institutes of Health, Bethesda, Maryland.
None:
What the article teaches Transcatheter heart valve thrombosis in the mitral position causes increased valve gradients, valve dysfunction, and symptoms, and may be associated with lack of therapeutic anticoagulation. How it will impact practice Anticoagulation with a vitamin K antagonist should be considered in all patients undergoing transcatheter mitral valve replacement. What new research/study would help answer the question posed Efficacy, optimal duration, and safety of anticoagulation therapy, balancing reduced thrombosis against increased bleeding risk, needs to be assessed in larger cohort studies and prospective trials.
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