[RISK FACTORS AND SPECIAL ASPECTS FORGENITAL TUBERCULOSIS DIAGNOSTICS].

Area of Science:

• Gynecology
• Infectious Diseases
• Medical Diagnostics

Background:

• Genital tuberculosis (GTB) is a significant concern, particularly in women presenting for diagnosis.
• Understanding GTB's prevalence and associated risk factors is crucial for early detection and management.
• Previous reproductive organ diseases, sexually transmitted diseases (STDs), and pregnancy complications are identified risk factors.

Purpose of the Study:

• To investigate the prevalence of genital tuberculosis in women seeking diagnostic evaluation.
• To identify key risk factors associated with the development of GTB.
• To evaluate the diagnostic accuracy of various laboratory methods, including PCR, for GTB detection.

Main Methods:

• A study involving 453 women undergoing genital tuberculosis diagnostics.
• Analysis of risk factors such as previous reproductive organ diseases, STDs, and pregnancy history.
• Evaluation of diagnostic tests: cytological, bacteriological, morphological, and PCR, assessing sensitivity and specificity.

Main Results:

• Genital tuberculosis was detected in 289 out of 453 women (approximately 63.8%).
• Significant risk factors identified include intracellular infections, STDs, and history of abortions.
• PCR diagnostics demonstrated high sensitivity (77.98%) and specificity (82.11%), outperforming other methods in combined accuracy.

Conclusions:

• Genital tuberculosis is prevalent in women presenting for diagnostics, with numerous associated risk factors.
• Specific symptoms like abdominal pain, dysmenorrhea, and findings such as hydrosalpinx are indicative of GTB.
• PCR offers a reliable diagnostic tool for genital tuberculosis, balancing both sensitivity and specificity effectively.