Serum vitamin D and recurrent benign paroxysmal positional vertigo

Area of Science:

• Otolaryngology
• Endocrinology
• Neurology

Background:

• Benign paroxysmal positional vertigo (BPPV) is a common vestibular disorder.
• The recurrence rate of BPPV can be significant, impacting patient quality of life.
• The role of vitamin D in BPPV pathogenesis and recurrence is not fully understood.

Purpose of the Study:

• To investigate the association between serum 25-hydroxyvitamin D concentrations and the recurrence of BPPV.
• To determine if vitamin D levels are an independent risk factor for BPPV recurrence.

Main Methods:

• Retrospective case series involving 232 patients diagnosed with BPPV.
• Patients were evaluated otolaryngologically, audiological, and neurologically.
• Serum vitamin D levels were compared between patients with and without BPPV recurrence using binary logistic regression.

Main Results:

• 17.7% of patients experienced BPPV recurrence within a 10.2-month follow-up period.
• Mean vitamin D levels were significantly lower in the recurrence group (13.64 ng/mL) compared to the non-recurrence group (16.63 ng/mL) (P < 0.019).
• Age, gender, follow-up duration, and BPPV type did not significantly influence recurrence.

Conclusions:

• Serum vitamin D deficiency is associated with an increased risk of BPPV recurrence.
• Vitamin D may act as an independent factor influencing BPPV recurrence, irrespective of other demographic or clinical factors.
• Maintaining adequate vitamin D levels could be a potential strategy for managing BPPV recurrence.