Related Experiment Video
Updated: Feb 22, 2026

3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects
Published on: August 4, 2020
Skull Reconstruction with Custom Made Three-Dimensional Titanium Implant.
Hyung Rok Cho1, Tae Suk Roh1, Kyu Won Shim2
1Department of Plastic and Reconstructive Surgery, Institute for Human Tissue Restoration, Yonsei University College of Medicine, Seoul, Korea.
This study explored the use of 3D-printed porous titanium implants for repairing large calvarial defects. Three patients with skull defects due to trauma or meningioma received custom implants made using 3D CT scans and electron beam melting. The implants were designed to fit each patient's skull precisely and secured with 8 mm screws. Postoperative scans showed correct implant positioning and no complications. The authors suggest that this method may offer a durable and accurate alternative to traditional reconstruction techniques.
Area of Science:
- Neurosurgical reconstruction techniques
- Medical 3D printing applications
- Cranioplasty material science
Background:
Calvarial defects present a clinical challenge due to their impact on cranial structure and function. Current reconstruction options include autologous bone grafts and synthetic materials. Autologous bone remains the gold standard due to its biocompatibility and integration potential. However, limitations such as donor site complications and insufficient volume restrict its use in large defects. Synthetic alternatives have been explored but often fall short in terms of structural integrity and adaptability. This gap motivated the development of patient-specific implants. Customization allows for better anatomical fit and reduces surgical time. The need for a durable and adaptable material led to the evaluation of titanium. 3D printing has enabled the fabrication of implants tailored to individual anatomical requirements. This approach addresses the limitations of traditional methods while offering a more precise solution.
Purpose Of The Study:
This study aimed to evaluate the feasibility and outcomes of using 3D-printed porous titanium implants for calvarial reconstruction. The specific problem addressed was the lack of suitable materials for large calvarial defects. Traditional methods often fail to provide the necessary structural support and anatomical fit. The motivation for this study stemmed from the need to improve surgical outcomes and reduce complications. Custom implants were proposed as a potential solution. The study focused on three patients with calvarial defects of varying sizes and locations. The goal was to assess the precision, fit, and postoperative stability of the implants. By using patient-specific 3D models, the team aimed to achieve a more accurate reconstruction. The study also sought to evaluate the healing process and implant positioning.
Main Methods:
The study involved three patients with calvarial defects caused by traumatic subdural hematoma or meningioma. Each patient underwent a CT scan to obtain 3D anatomical data. The CT data was processed using Mimics software to create a digital model of the defect. The design of the titanium implant was based on this model. Multiple implant designs were tested using 3D-printed skull replicas. The final implant was fabricated using an electron beam melting machine. The porous structure of the titanium was designed to promote tissue integration. During surgery, the implant was placed over the defect and secured with 8 mm screws. Postoperative CT scans were used to assess implant positioning and integration. The surgical outcomes were evaluated for complications and healing progress.
Main Results:
All three patients received 3D-printed porous titanium implants tailored to their specific calvarial defects. The implants were placed without dead space and achieved a precise anatomical fit. Rigid fixation with 8 mm screws ensured stability during the healing process. Postoperative CT scans confirmed the correct positioning of the implants. No surgical complications were reported in any of the cases. The operative sites healed without infection or other adverse events. The porous structure of the titanium implants allowed for tissue integration. The implants provided the necessary structural support and durability. The use of 3D-printed titanium eliminated the need for autologous grafts in these cases. The results suggest that this method is a viable alternative to traditional reconstruction techniques.
Conclusions:
The study demonstrated that 3D-printed porous titanium implants can be used effectively for calvarial reconstruction. The authors suggest that this method offers a precise and durable solution for large defects. The implants fit the anatomical contours of the skull without dead space. The use of 3D imaging and printing allowed for customization to individual patient needs. The authors propose that this approach may reduce the need for autologous grafts. The study suggests that titanium implants provide sufficient structural support. The authors note that the porous design may promote tissue integration. The results suggest that this method is a promising alternative to traditional techniques.
Frequently Asked Questions
The main advantage is the ability to create patient-specific implants that fit precisely into the defect without dead space.
The implants were designed using individual 3D CT data processed with Mimics software and fabricated via electron beam melting.
The porous structure was selected to promote tissue integration and improve long-term stability of the implant.
They were used to evaluate multiple implant designs before final fabrication to ensure a precise fit.
The implants were fixed using 8 mm screws to ensure rigid stabilization during healing.
The authors suggest that this method may become a viable alternative to traditional autologous grafts for large calvarial defects.

