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Updated: Feb 22, 2026

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Semi-Minimal Invasive Method to Induce Myocardial Infarction in Rats and the Assessment of Cardiac Function by an Isolated Working Heart System
Published on: June 11, 2020
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Changes in Sympathetic Innervation of the Heart in Rats with Experimental Myocardial Infarction. Effect of Semax
S A Gavrilova1, M A Markov1, A B Berdalin2
1Department of Physiology and General Pathology, Faculty of Fundamental Medicine, M. V. Lomonosov Moscow State University, Moscow, Russia.
Bulletin of Experimental Biology and Medicine
|September 27, 2017
Abstract:
The effect of peptide Semax on remodeling of cardiac sympathetic innervation was examined in rats with experimental myocardial infarction. In 28 days after ischemia/reperfusion injury, Semax diminished the growth of sympathetic innervation of ventricular septum, although it produced no effect on the density of β1 and β2 adrenoceptors.

