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Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
Published on: October 18, 2011
Cognitive Changes Related to Cancer Therapy.
1Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 218, Baltimore, MD 21287, USA; Department of Neurology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 218, Baltimore, MD 21287, USA.
Cancer survivors may experience long-term cognitive impairment (CRCI), affecting memory and attention. Neuropsychological assessment can identify issues and guide interventions to improve cognitive function and quality of life.
Area of Science:
- Oncology
- Neuroscience
- Psychology
Background:
- Cancer survivors face risks of acute and long-term side effects from cancer and its treatment.
- Cancer-related cognitive impairment (CRCI) presents as deficits in attention, processing speed, executive functioning, and memory, potentially lasting decades.
- While some CRCI risk factors are immutable, others are modifiable, offering opportunities for intervention.
Purpose of the Study:
- To highlight the prevalence and impact of CRCI in cancer survivors.
- To discuss the role of neuropsychological assessment in understanding and managing CRCI.
- To emphasize the potential for improving cognitive function and quality of life through targeted interventions.
Main Methods:
- Review of existing literature on cancer-related cognitive impairment.
- Discussion of neuropsychological assessment techniques for identifying cognitive deficits.
- Exploration of psychological and behavioral contributors to CRCI.
Main Results:
- CRCI is a common and persistent issue for cancer survivors.
- Neuropsychological assessment is crucial for diagnosing specific cognitive weaknesses.
- Modifiable factors contribute to CRCI, suggesting avenues for therapeutic strategies.
Conclusions:
- Neuropsychological assessment aids in identifying cognitive strengths and weaknesses in cancer survivors.
- Targeting psychological and behavioral factors can mitigate CRCI.
- Interventions guided by assessment can improve cognitive function and quality of life for cancer survivors.
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