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Recent advances in in vitro fertilization
Robert Casper1,2,3, Jigal Haas1, Tzu-Bou Hsieh1
1Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Toronto and TRIO Fertility, Toronto, Ontario, Canada.
F1000Research
|October 14, 2017
Summary
This review covers advances in assisted reproductive technology, focusing on improving oocyte quality in older women and new in vitro fertilization protocols. It also examines pre-implantation genetic screening and endometrial receptivity methods.
Area of Science:
- Reproductive Medicine
- In Vitro Fertilization
Background:
- Assisted reproductive technology (ART) has seen significant advancements in the past decade.
- Improving outcomes in in vitro fertilization (IVF) remains a key focus in reproductive medicine.
Purpose of the Study:
- To review recent technological advancements in ART.
- To discuss methods for enhancing oocyte quality in older women.
- To explore novel stimulation protocols and assess endometrial receptivity techniques.
Main Methods:
- Literature review of recent studies and technological developments in ART.
- Discussion of current practices and emerging technologies in IVF.
- Analysis of pre-implantation genetic screening (PGS) applications.
Main Results:
- New stimulation protocols may increase mature oocyte retrieval in IVF cycles.
- Emerging methods for determining endometrial receptivity are being investigated.
- Pre-implantation genetic screening (PGS) is a current area of focus.
Conclusions:
- Several new technologies in ART require further controlled studies for validation.
- Focus on improving oocyte quality and IVF protocols can enhance success rates.
- Understanding endometrial receptivity is crucial for successful implantation.
Related Concept Videos
Fertilization
During fertilization, an egg and sperm cell fuse to create a new diploid structure. In humans, the process occurs once the egg has been released from the ovary, and travels into the fallopian tubes. The process requires several key steps: 1) sperm present in the genital tract must locate the egg; 2) once there, sperm need to release enzymes to help them burrow through the protective zona pellucida of the egg; and 3) the membranes of a single sperm cell and egg must fuse, with the sperm...
In Vitro Fertilization
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...

