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THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes
Stephen Ph Alexander1, Doriano Fabbro2, Eamonn Kelly3
1School of Life Sciences, University of Nottingham Medical School, Nottingham, NG7 2UH, UK.
British Journal of Pharmacology
|October 22, 2017
Summary
The Concise Guide to Pharmacology 2017/18 offers a summary of 1800 drug targets, including enzymes and receptors. This guide provides essential pharmacology information and links to a comprehensive online knowledgebase.
Area of Science:
- Pharmacology
- Drug Discovery
- Biochemistry
Background:
- The Concise Guide to Pharmacology is a key resource for understanding drug targets.
- Previous editions have been published biennially.
- The 2017/18 edition updates information on human drug targets.
Purpose of the Study:
- To provide a concise overview of nearly 1800 human drug targets.
- To emphasize selective pharmacology and link to an open-access knowledgebase.
- To offer a permanent, citable record of drug target information.
Main Methods:
- Compilation of data on drug targets, including enzymes, receptors, and ion channels.
- Emphasis on selective pharmacology where available.
- Inclusion of nomenclature guidance and references.
Main Results:
- Overview of approximately 1800 human drug targets.
- Detailed information on enzymes, G protein-coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors, and transporters.
- Links to an open-access knowledgebase for further details.
Conclusions:
- The Concise Guide to Pharmacology 2017/18 serves as a valuable, up-to-date reference for drug targets.
- It facilitates comparison of related targets and provides official IUPHAR classification.
- The guide is a permanent, citable resource for researchers.
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