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Formulation and Characterization of Bioactive Agent Containing Nanodisks
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Design of Nanosomal Form of Aprotinin
O A Kulikov1, N A Pyataev1, A V Zaborovskii2
1N. P. Ogarev Mordovia National Research State University, Saransk, the Republic of Mordovia, Russia.
Bulletin of Experimental Biology and Medicine
|October 25, 2017
Abstract:
Liposomes containing aprotinin were produced by the phase inversion technique and purified by gel filtration. Aprotinin inclusion was assessed fluorescence labeling of the protein. The size of obtained liposomes was 212±35 nm and aprotinin concentration in the liposomal suspension was 3000 KIU/ml. The efficiency of aprotinin inclusion into liposomes was 31.9%.
