Related Experiment Video For Ancillary testing
Updated: Feb 18, 2026
Brain Death Induction in Mice Using Intra-Arterial Blood Pressure Monitoring and Ventilation via Tracheostomy
Published on: April 17, 2020
Brain Death
Mack Drake1, Andrew Bernard1, Eugene Hessel2
1Section on Trauma and Acute Care Surgery, Division of General Surgery, Department of Surgery, University of Kentucky College of Medicine, C224, 800 Rose Street, Lexington, KY 40536-0298, USA.
Abstract:
Death determined by neurologic criteria, commonly referred to as "brain death," occurs when function of the entire brain ceases, including the brain stem. Diagnostic criteria for brain death are explicit but controversy exists regarding nuances of the evaluation and potential confounders of the examination. Hospitals and ICU teams should carefully consider which clinicians will perform brain death testing and should use standard processes, including checklists to prevent diagnostic errors. Proper diagnosis is essential because misdiagnosis can be catastrophic. Timely, accurate brain death determination and aggressive physiologic support are cornerstones of both good end-of-life care and successful organ donation.
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