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Updated: Feb 18, 2026
A Novel and Translational Rat Model of Concussion Combining Force and Rotation with In Vivo Cerebral Microdialysis
Published on: July 12, 2019
Imaging the Role of Myelin in Concussion
Alexander Mark Weber1, Carlos Torres2, Alexander Rauscher1
1Department of Pediatrics, Division of Neurology, Faculty of Medicine, University of British Columbia, M10 - Purdy Pavilion, 2221 Wesbrook Mall, Vancouver, British Columbia V6T 2B5, Canada.
Abstract:
Myelin water imaging (MWI) provides mild traumatic brain injury (mTBI) researchers with a specific myelin biomarker and helps to further elucidate microstructural and microarchitectural changes of white matter after mTBI. Improvement of scanner hardware and software with the implementation of MWI across scanner platforms will likely result in increased research regarding the role of myelin in traumatic brain injury (TBI). Future research should include detailed investigation of myelin between 2 weeks and 2 months after injury, the use of MWI in moderate and severe TBI, and investigation of the role of myelin in chronic TBI.
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