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Dysrhythmias with Loperamide Used for Opioid Withdrawal

Nicki D Vithalani1, Christopher Heron2, Ravishankar E Rao2

  • 1From the Penn State Health, State College, PA (NDV, CH, RER, MBS); Mount Nittany Physician Group, State College (AFC). nvithalanimd@gmail.com.

Journal of the American Board of Family Medicine : JABFM
|November 29, 2017
PubMed
Summary

High-dose loperamide, an antidiarrheal, is increasingly used for opioid withdrawal. This misuse can lead to severe cardiac events and death, as seen in a case of a young woman experiencing collapse.

Keywords:
Cardiovascular SystemCommunity MedicineLoperamideOpioidsPatient CarePrimary Health CareSubstance Withdrawal SyndromeTorsades de PointesToxicity

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