Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Regulation of Food Intake

Regulation of Food Intake

Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...

Neurotransmitters

Neurotransmitters

Neurotransmitters are essential chemical messengers within the nervous system, facilitating the communication between neurons. These chemical messengers, varying in function and effect, are critical for sustaining various aspects of neurological health and emotional well-being.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A retrospective study of prostate cancer cases mimicking urothelial cell carcinoma of the bladder.

European journal of medical research·2013

Same author

High expression of nucleobindin 2 mRNA: an independent prognostic factor for overall survival of patients with prostate cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine·2013

Same author

Impact of stone branch number on outcomes of percutaneous nephrolithotomy for treatment of staghorn calculi.

Journal of endourology·2013

Same author

Analysis of microRNA expression profile by small RNA sequencing in Down syndrome fetuses.

International journal of molecular medicine·2013

Same author

Campylobacter jejuni colonization is associated with a dysbiosis in the cecal microbiota of mice in the absence of prominent inflammation.

PloS one·2013

Same author

[Value of contrast-enhanced ultrasound (CEUS) in the differential diagnosis between benign and malignant renal neoplasms].

Zhonghua zhong liu za zhi [Chinese journal of oncology]·2013

Same journal

Mammalian Respiratory Chain Complex Assemblies and Their Links to Mitochondria Stress-Induced Human Diseases.

Advances in experimental medicine and biology·2026

Same journal

Enzyme Assemblies in Nucleotide Metabolism: Structure, Regulation, and Disease Implications.

Advances in experimental medicine and biology·2026

Same journal

The Pyruvate Dehydrogenase Complex: A 90-Year-Old Enigma Shaping the Future of Structural Enzymology.

Advances in experimental medicine and biology·2026

Same journal

Regulation of the Anti-termination RNA Transcription Complex by Lon-Mediated Lambda N Degradation.

Advances in experimental medicine and biology·2026

Same journal

PCNA Macromolecular Complexes: PCNA Serves as a Molecular Hub Regulating Multiple Cellular Processes Inside and Outside of the Nucleus.

Advances in experimental medicine and biology·2026

Same journal

Dynamic Assemblies in Genome Maintenance.

Advances in experimental medicine and biology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Feb 17, 2026

Protocol for Studying Extinction of Conditioned Fear in Naturally Cycling Female Rats

Protocol for Studying Extinction of Conditioned Fear in Naturally Cycling Female Rats

Published on: February 23, 2015

Brain Estrogens and Feeding Behavior.

¹USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA. yongx@bcm.edu.

Advances in Experimental Medicine and Biology

|December 11, 2017

Summary

This summary is machine-generated.

Estrogens help control appetite and body weight. Understanding how brain estrogens interact with other signals and receptors could lead to new obesity treatments.

More Related Videos

Assessing Cellular Stress and Inflammation in Discrete Oxytocin-secreting Brain Nuclei in the Neonatal Rat Before and After First Colostrum Feeding

Assessing Cellular Stress and Inflammation in Discrete Oxytocin-secreting Brain Nuclei in the Neonatal Rat Before and After First Colostrum Feeding

Published on: November 14, 2018

Fat Preference: A Novel Model of Eating Behavior in Rats

Fat Preference: A Novel Model of Eating Behavior in Rats

Published on: June 27, 2014

Related Experiment Videos

Last Updated: Feb 17, 2026

Protocol for Studying Extinction of Conditioned Fear in Naturally Cycling Female Rats

Protocol for Studying Extinction of Conditioned Fear in Naturally Cycling Female Rats

Published on: February 23, 2015

Assessing Cellular Stress and Inflammation in Discrete Oxytocin-secreting Brain Nuclei in the Neonatal Rat Before and After First Colostrum Feeding

Assessing Cellular Stress and Inflammation in Discrete Oxytocin-secreting Brain Nuclei in the Neonatal Rat Before and After First Colostrum Feeding

Published on: November 14, 2018

Fat Preference: A Novel Model of Eating Behavior in Rats

Fat Preference: A Novel Model of Eating Behavior in Rats

Published on: June 27, 2014

Area of Science:

Neuroendocrinology
Obesity Research
Molecular Biology

Background:

Estrogens are crucial for regulating food intake and body weight.
Estrogen receptors and signaling pathways are key targets for obesity therapies.
Brain-based estrogenic signals significantly influence feeding behavior.

Purpose of the Study:

To explore the interplay between brain estrogens and appetite-regulating signals.
To identify critical estrogen receptor isoforms and brain regions mediating estrogenic effects on feeding.
To elucidate the intracellular signaling mechanisms involved in estrogen-controlled feeding.

Main Methods:

Review of existing literature on estrogenic regulation of feeding.
Analysis of functional interactions between estrogenic and other neurochemical systems.
Examination of specific estrogen receptor subtypes and their localization in the brain.
Investigation of downstream intracellular signaling cascades.

Main Results:

Estrogens interact functionally with various appetite-regulatory signals in the brain.
Specific estrogen receptor isoforms (e.g., ERα) and distinct brain nuclei (e.g., hypothalamus) are critical for mediating anti-feeding effects.
Intracellular pathways involving kinases and transcription factors are activated by brain estrogens to influence energy balance.

Conclusions:

Brain estrogens are integral components of the appetite control network.
Targeting specific estrogen pathways in the brain offers a promising strategy for developing novel anti-obesity medications.
Further research into estrogen receptor signaling in the brain is warranted for therapeutic advancements.