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Updated: Jun 24, 2026

Genome-wide Protein-protein Interaction Screening by Protein-fragment Complementation Assay (PCA) in Living Cells
08:38

Genome-wide Protein-protein Interaction Screening by Protein-fragment Complementation Assay (PCA) in Living Cells

Published on: March 3, 2015

PCNA Macromolecular Complexes: PCNA Serves as a Molecular Hub Regulating Multiple Cellular Processes Inside and

Hamsini Kala1, Dana Abou Abbas2, Linda H Malkas3

  • 1Irell & Manella Graduate School of Biological Sciences, Department of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, CA, USA.

Advances in Experimental Medicine and Biology
|June 23, 2026
PubMed
Abstract

Keywords:
Cancer-associated PCNA isoformDNA replication and repairGenome stabilityImmune surveillancePost-translational modificationsProliferating cell nuclear antigenProtein-protein interactionsReplication stressSmall-molecule inhibitors

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