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[MODERN APPROACHES TO DIAGNOSIS AND TREATMENT OF TUMORS OF FEMALE GENITALS OF CHILDREN AND ADOLESCENTS (REVIEW)]
A Solopova1, A Makatsaryia1, O Yakovleva1
1Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Department of Obstetrics & Gynaecology of the Public Health Faculty, Moscow, Russia.
This review covers pediatric female genital tumors, focusing on ovarian germ cell tumors. Early diagnosis and current treatments, including surgery and chemotherapy, help preserve reproductive health in girls.
Area of Science:
- Gynecology
- Pediatric Oncology
- Oncopathology
Background:
- Pediatric female genital tumors require specialized diagnostic and treatment approaches.
- Ovarian germ cell tumors are a significant concern in this age group.
- Understanding epidemiology, morphology, and clinical presentation is crucial.
Purpose of the Study:
- To summarize current knowledge on pediatric female genital tumors.
- To highlight diagnostic and therapeutic strategies, with emphasis on ovarian germ cell tumors.
- To review the latest research on epidemiology, morphology, clinical course, and treatment.
Main Methods:
- Comprehensive literature review of domestic and foreign publications.
- Analysis of epidemiological data, morphological characteristics, and clinical manifestations.
- Evaluation of modern diagnostic and treatment principles.
Main Results:
- Immunohistochemistry and tumor markers aid in diagnosing malignant ovarian germ cell tumors.
- Standard treatment involves surgical removal of affected appendages, chemotherapy, and radiation therapy.
- Effective management strategies are essential for preserving reproductive function.
Conclusions:
- Timely diagnosis and appropriate treatment are vital for pediatric patients with female genital tumors.
- Current therapeutic modalities aim to maximize cure rates while minimizing long-term sequelae.
- Preservation of reproductive potential is a key consideration in treatment planning.
