EFFICACY OF OSSEIN-HYDROXYAPATITE COMPLEX AS A PHARMACOLOGICAL CORRECTOR OF BONE LOSS (REVIEW)

Area of Science:

• Bone biology and pharmacology
• Osteoporosis research
• Pharmacological interventions for bone health

Background:

• Osteoporosis is a global health concern with complex bone mass regulation.
• Pharmacological interventions are expanding to address bone density issues.
• The ossein-hydroxyapatite complex (OHC) is under consideration for treating osteopenia and osteoporosis.

Purpose of the Study:

• To review the literature on the use of ossein-hydroxyapatite complex (OHC) for bone health.
• To explore OHC's effectiveness and safety in various clinical scenarios.
• To identify unresolved issues regarding OHC application in clinical practice.

Main Methods:

• Literature review of studies on ossein-hydroxyapatite complex (OHC).
• Analysis of OHC's role in traumatology, hormonal imbalances, and age-related bone conditions.
• Examination of experimental data on OHC's mechanisms of action.

Main Results:

• OHC demonstrates potential benefits in managing complicated fractures and bone imbalances.
• Its effects are considered in contexts of hormonal dysregulation and long-term glucocorticoid therapy.
• OHC's positive impact on bone cells and tissue is supported by experimental findings.

Conclusions:

• OHC is a promising agent for pharmacological correction of bone tissue imbalances.
• Further clarification is required on optimal dosing, therapy duration, and personalized indications for OHC.
• Unresolved aspects of OHC clinical protocols need addressing for personalized medicine.