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The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
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OPTN/SRTR 2016 Annual Data Report: Lung.

M Valapour1,2, C J Lehr2, M A Skeans1

  • 1Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN.

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
|January 3, 2018
PubMed
Summary
This summary is machine-generated.

Lung transplant waiting times decreased in 2016, with improved short-term survival rates for recipients. The revised lung allocation score (LAS) shows early positive trends in waitlist dynamics and transplant outcomes.

Keywords:
LASEnd-stage lung diseaselung allocation scorelung transplantorgan allocationrevised lung allocation scoretransplant outcomes

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Area of Science:

  • Cardiology and Thoracic Surgery
  • Transplantation Medicine
  • Health Services Research

Background:

  • In 2016, lung transplantation saw record numbers, with 2692 candidates added to the waiting list and 2345 transplants performed.
  • The median waiting time for lung transplant candidates in 2016 was 2.5 months, with shortest waits for group D candidates.

Purpose of the Study:

  • To analyze lung transplant waiting list dynamics and outcomes in 2016.
  • To evaluate the impact of the revised lung allocation score (LAS) implemented in 2015 on transplant trends.

Main Methods:

  • Analysis of national lung transplant waiting list data from 2016.
  • Comparison of survival rates and waitlist mortality before and after the 2015 LAS revision.

Main Results:

  • The transplant rate increased to 191.9 per 100 waitlist years, while waitlist mortality slightly decreased to 15.1 per 100 waitlist years.
  • Short-term survival improved, with 6-month and 1-year death rates at 6.6% and 10.8% for 2015 recipients, respectively.
  • Early trends suggest the revised LAS is associated with shorter waiting times and a stabilization of candidates with high LAS scores.

Conclusions:

  • The revised lung allocation score (LAS) shows promising early effects on lung transplant waitlist management and patient outcomes.
  • Continued monitoring is essential to fully understand the long-term impact of the LAS revision on lung transplantation.