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Updated: Feb 16, 2026
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Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
Published on: September 29, 2017
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Electrochemical antioxidant screening based on a chitosan hydrogel
Li Fu1, Aiwu Wang2, Fucong Lyv2
1Collage of Materials and Environmental Engineering, Hangzhou Dianzi University, Hangzhou 310018, PR China.
Bioelectrochemistry (Amsterdam, Netherlands)
|January 7, 2018
Summary
A novel chitosan hydrogel detects antioxidants by monitoring silver
Area of Science:
- Materials Science
- Biochemistry
- Analytical Chemistry
Background:
- Chitosan hydrogels are versatile biomaterials.
- Silver ions can be complexed within hydrogels.
- Hydroxyl radicals can influence silver's redox state.
Purpose of the Study:
- To develop a hydrogel-based sensor for antioxidant capacity evaluation.
- To utilize the interaction between hydroxyl radicals and chitosan-silver hydrogels.
Main Methods:
- Fabrication of a chitosan hydrogel crosslinked with silver ions.
- Investigating the effect of hydrogen peroxide-induced hydroxyl radicals on the hydrogel.
- Monitoring the restoration of silver redox behavior as an indicator.
Main Results:
- Silver redox behavior was suppressed in the chitosan hydrogel.
- Hydroxyl radicals restored silver redox behavior by interacting with glucoside bonds.
- This mechanism was successfully used to evaluate antioxidant capacity.
Conclusions:
- The developed hydrogel sensing platform offers a low-cost and portable method for antioxidant screening.
- The platform avoids the need for electrode modification, simplifying its application.
- This approach shows significant potential for rapid antioxidant capacity evaluation.
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