Related Experiment Video
Updated: Feb 15, 2026

09:29
Stereotactically-guided Ablation of the Rat Auditory Cortex, and Localization of the Lesion in the Brain
Published on: October 11, 2017
12.2K
Stereotactic Radiofrequency Lesioning for Movement Disorders
Progress in Neurological Surgery
|January 15, 2018
Summary
Radiofrequency (RF) lesioning, once considered outdated, is a safe and effective treatment for movement disorders when using modern stereotactic techniques. Neurosurgeons can now choose between RF lesioning and deep brain stimulation (DBS) for optimal patient care.
Area of Science:
- Neurosurgery
- Neurology
- Medical Devices
Background:
- Deep brain stimulation (DBS) has largely replaced radiofrequency (RF) lesioning for movement disorders over the past 20 years.
- RF lesioning is often perceived as outdated and dangerous due to historical stereotactic techniques.
- Current DBS therapy involves hardware complications and symptom management, with the device posing a burden to patients.
Purpose of the Study:
- To re-evaluate the safety and efficacy of RF lesioning for movement disorders.
- To compare modern RF lesioning techniques with current DBS therapy.
- To inform neurosurgeons about the viable therapeutic options for movement disorder patients.
Main Methods:
- Review of historical and modern stereotactic techniques.
- Analysis of complication rates and long-term outcomes for both RF lesioning and DBS.
- Assessment of indications for RF lesioning in various movement disorders.
Main Results:
- Modern stereotactic techniques render RF lesioning a safe and effective procedure.
- RF lesioning is indicated for various tremors, focal hand dystonia, and generalized or segmental dystonias.
- DBS, while effective, has hardware-related complications and only manages symptoms.
Conclusions:
- RF lesioning remains a valuable and safe treatment option for specific movement disorders.
- Neurosurgeons should consider both RF lesioning and DBS to select the optimal treatment for individual patients.
- Advancements in stereotactic technology have revitalized RF lesioning as a viable neurosurgical intervention.
Related Concept Videos
Anatomical Movements
16.4K
Anatomical movements refer to the various actions or motions that can be performed by the body's joints and muscles. These movements are described using specific terms to provide a standardized way of discussing and understanding the range of motion at different joints.
Here are some common anatomical movements:
Flexion and extension motions are in the sagittal (anterior–posterior) plane of motion. These movements take place at the shoulder, hip, elbow, knee, wrist,...
Here are some common anatomical movements:
Flexion and extension motions are in the sagittal (anterior–posterior) plane of motion. These movements take place at the shoulder, hip, elbow, knee, wrist,...
16.4K
Intrinsically Disordered Proteins
19.6K
Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
19.6K
The Movement of Organelles and Vesicles
6.6K
In eukaryotic cells, cytoskeletal filaments such as actin, microtubules, and intermediate filaments form a mesh-like cytoskeletal network. These filaments serve as tracks for transporting cellular cargo. Specialized motor proteins use the chemical energy stored in adenosine triphosphate (ATP) for this transport. During interphase, microtubules are polarized, with the plus-end towards the cell periphery and the minus-end towards the cell center. Two microtubule-associated motor proteins,...
6.6K
NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences
1.8K
A pulse is a short burst of radio waves distributed over a range of frequencies that simultaneously excites all the nuclei in the sample. Upon passing a radio frequency pulse along the x-axis, the nuclei absorb energy corresponding to their Larmor frequencies and achieve resonance. This shifts the net magnetization vector from the z-axis toward the transverse plane. This angle of rotation of the magnetization vector, or the flip angle, is proportional to the duration and intensity of the pulse.
1.8K
Fluid Movement Between Compartments
4.2K
The force applied by fluids against a surface, known as hydrostatic pressure, initiates the transfer of fluid among different compartments. Within our blood vessels, the blood's hydrostatic pressure is a result of the heart's pumping action. At the arteriolar end of capillaries, hydrostatic pressure (capillary blood pressure) exceeds the opposing colloid osmotic pressure created primarily by plasma proteins like albumin. This discrepancy in pressure propels plasma and nutrients from the...
4.2K
Movement Joints in Buildings
364
Movement joints in buildings are essential design elements that accommodate inevitable motions caused by various factors such as temperature changes, moisture content variations, and structural deflections. These motions, if not considered in design and construction, can lead to unsightly or dangerous damage. Movement joints are incorporated in different forms to manage these stresses and allow materials to move without causing distress.
The simplest type of movement joints, working joints, are...
The simplest type of movement joints, working joints, are...
364

