Related Experiment Video
Updated: Feb 15, 2026

Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay
Published on: March 12, 2018
A Rare Case of Metastatic Choriocarcinoma of Lung Origin
Parth Rali1, Jianwu Xie2, Grishma Rali3
1Division of Pulmonary and Critical Care, Allegheny General Hospital, Pittsburgh, PA 15212, USA.
Abstract:
Choriocarcinoma is part of the spectrum of gestational trophoblastic disease that occurs in women of reproductive age. Although the most common metastatic site of choriocarcinoma is the lung, primary pulmonary choriocarcinoma is rare. To diagnose primary pulmonary choriocarcinoma, the patient should have no previous gynecologic malignancy, have elevated human chorionic gonadotropin, and have pathological confirmation of the disease excluding gonadal primary site of the tumor. Due to the paucity of data, there are no guidelines for treatment. Prognosis of this malignancy is extremely poor. We report a rare case of metastatic primary lung choriocarcinoma in a 69-year-old postmenopausal woman who was treated with combination of surgery, chemotherapy, and radiation. The patient had a good outcome and is doing well after 1-year follow-up.
Related Concept Videos
Lung Capacity
Cancers Originate from Somatic Mutations in a Single Cell
Pleura of the Lungs
Gross Anatomy of the Lungs
Genome Size and the Evolution of New Genes
Frequency-dependent Selection

