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Published on: February 20, 2020
Dearylation of arylphosphine oxides using a sodium hydride-iodide composite
Ciputra Tejo1, Jia Hao Pang, Derek Yiren Ong
1Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore. shunsuke@ntu.edu.sg.
Abstract:
A new protocol for the dearylation of arylphosphine oxides was developed using sodium hydride (NaH) in the presence of lithium iodide (LiI). The transient sodium phosphinite could be functionalized with a range of electrophiles in a one-pot fashion.
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