Related Experiment Video
Updated: Feb 14, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Preparticipation Screening of Young Athletes: Identifying Cardiovascular Disease
Kyle P Lammlein1, Jonathan M Stoddard1, Francis G O'Connor2
1Family Medicine, National Capital Consortium Family Medicine Residency, Fort Belvoir Community Hospital, 9300 DeWitt Loop, Fort Belvoir, VA 22060, USA.
Abstract:
The most common cause of sudden cardiac death (SCD) in young athletes in the United States is "autopsy-negative sudden unexplained death." This makes it extremely difficult to screen for and diagnose predisposing cardiovascular conditions before athletic participation. The goal of the preparticipation physical examination is to detect risk factors for SCD, make risk-based decisions regarding the need for further workup, and ultimately recommend for or against participation. Current evidence recommends universal screening of young athletes using the 14-point American Heart Association preparticipation cardiovascular checklist. Electrocardiograms and echocardiograms are not currently recommended in the United States to screen athletes.
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