Related Experiment Video
Updated: Feb 14, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Swept-Source OCT Angiography of Full-Thickness Macular Holes: Appearance and Artifacts
Background And Objective:
To evaluate swept-source optical coherence tomography angiography (SS-OCTA) images in full-thickness macular holes (FTMHs).
Patients And Methods:
SS-OCTA of FTMHs was performed before or after surgery. Vitrectomy with the temporal inverted internal limiting membrane flap technique was used. The authors measured the diameter and area of the foveal avascular zone (FAZ) in superficial and deep retina vasculature.
Results:
In 88 patients, two artifact types were observed. First, a hyperreflective circle in the center corresponding to a segmentation failure, as in these cases the segmentation line automatically relocated below the retinal pigment epithelium. Second, in macular holes with cystic spaces around the fovea, detection of blood flow was only partially possible, showing artifacts in the perifoveal vasculature.
Conclusion:
The authors present artifacts occurring during visualization of FTMHs with SS-OCTA and the means to correct them. Eyes with decreased postoperative central retinal thickness have an increased FAZ in the deep retinal layer plexus. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:111-121.].
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