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Updated: Feb 13, 2026

Kidney Regeneration in Adult Zebrafish by Gentamicin Induced Injury
Published on: August 3, 2015
α-Tocopherol Reduces Morphological Changes and Oxidative Stress during Gentamicin-Induced Acute Renal Failure
N Stojiljkovic1, S Ilic2, M Veljkovic2
1Institute of Physiology, Nis, Serbia. nenstojiljkovic@gmail.com.
Abstract:
We studied the effect of α-tocopherol on gentamicin-induced morphological and functional changes in the kidneys of Wistar rats. Special attention was paid to the ability of α-tocopherol administered in combination with gentamicin to correct ultrastructural changes in the glomerular basal membrane and tubules. Combined treatment with α-tocopherol (100 mg/kg) and gentamicin (100 mg/kg) led to correction of histopathological and biochemical changes and oxidative injury to the kidneys induced by this antibiotic.
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