Related Experiment Video

Updated: Feb 13, 2026

Author Spotlight: Advancing Cancer Associated Thrombosis Research in Rodent Models
04:40

Author Spotlight: Advancing Cancer Associated Thrombosis Research in Rodent Models

Published on: January 5, 2024

3.3K

Catheter-Directed Therapy Options for Iliofemoral Venous Thrombosis

Deepak Sudheendra1, Suresh Vedantham2

  • 1Department of Radiology, University of Pennsylvania, Perelman School of Medicine, 1 Silverstein, 3400 Spruce Street, Philadelphia, PA 19104, USA.

The Surgical Clinics of North America
|March 6, 2018
PubMed

Insights

Proximal deep venous thrombosis (DVT) poses significant risks for pulmonary embolism and postthrombotic syndrome. Catheter-directed thrombolysis offers endovascular treatment options for iliofemoral DVT, with this review detailing associated risks, benefits, and techniques.

Area of Science:

  • Vascular Surgery
  • Interventional Radiology
  • Cardiology

Background:

  • Proximal deep venous thrombosis (DVT), specifically iliofemoral DVT, carries a high risk of serious complications.
  • These complications include a 50% risk of potentially life-threatening pulmonary embolism.
  • A 50% risk of debilitating postthrombotic syndrome also exists, impacting long-term quality of life.

Purpose of the Study:

  • To review current catheter-directed thrombolysis treatment options for iliofemoral DVT.
  • To discuss the risks and benefits associated with endovascular procedures for iliofemoral DVT.
  • To outline the techniques commonly employed in performing these endovascular interventions.

Main Methods:

  • Review of existing literature on catheter-directed thrombolysis for iliofemoral DVT.
  • Analysis of reported outcomes, including efficacy and complication rates.
  • Discussion of procedural techniques and patient selection criteria.

Main Results:

  • Catheter-directed thrombolysis is a viable endovascular option for selected patients with iliofemoral DVT.
  • The procedure aims to rapidly restore venous patency, potentially mitigating risks of PE and PTS.
  • Specific techniques and devices are utilized to optimize thrombus removal and minimize procedural complications.

Conclusions:

  • Catheter-directed thrombolysis represents an important therapeutic strategy for managing iliofemoral DVT.
  • Careful patient selection and procedural technique are crucial for maximizing benefits and minimizing risks.
  • Further research may refine indications and optimize outcomes for endovascular treatment of DVT.

Keywords:
Deep vein thrombosisIliac vein compressionMay Thurner syndromePostthrombotic syndromePulmonary embolism

More Related Videos

Electrolytic Inferior Vena Cava Model EIM of Venous Thrombosis06:03

Electrolytic Inferior Vena Cava Model EIM of Venous Thrombosis

Published on: July 12, 2011

17.8K
The Supraclavicular Fossa Ultrasound View for Central Venous Catheter Placement and Catheter Change Over Guidewire07:47

The Supraclavicular Fossa Ultrasound View for Central Venous Catheter Placement and Catheter Change Over Guidewire

Published on: December 23, 2014

20.2K

Related Concept Videos

Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
489
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
378
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
273
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
354
Venous Return01:04

Venous Return

The circulatory system plays a crucial role in ensuring the optimal functioning of the human body. One of its critical components is venous return - the process that completes the blood circulation cycle. This article will delve into the concept of venous return, how it works, and its significance to our health.
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
12.6K
Gene Therapy00:59

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.7K