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Updated: Feb 13, 2026
10:24
Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor
Published on: May 7, 2021
2.8K
Feasibility study on medical isotope production using a compact neutron generator
Ka-Ngo Leung1, James K Leung2, Graeme Melville3
1Nuclear Engineering Department, University of California, Berkeley, CA 94720, USA; Berkion Technology, Hercules, CA 94547, USA.
Summary
Compact neutron generators utilizing the D-7Li reaction can produce high neutron yields. This technology enables the efficient production of essential medical radioisotopes like 99Mo and 225Ac.
Area of Science:
- Nuclear Physics
- Medical Isotopes Production
Background:
- Compact neutron generators offer high neutron flux across a wide energy spectrum.
- Recent studies show significant neutron yields from the D-7Li fusion reaction at 500 keV.
Purpose of the Study:
- To evaluate the potential of D-7Li fusion reactions in compact neutron generators for radioisotope production.
- To assess the feasibility of producing medical radioisotopes using advanced neutron generator technology.
Main Methods:
- Utilizing the D-7Li fusion reaction with advanced high flux neutron generator technology.
- Leveraging commercial high voltage DC power supplies for generator operation.
- Estimating radioisotope yields based on known neutron reaction cross-sections.
Main Results:
- High neutron yields demonstrated from the D-7Li reaction at 500 keV.
- Estimated production of hundreds-to-thousands MBq of 99Mo, 225Ac, 64Cu, and 67Cu.
- Feasibility of producing useful quantities of medical radioisotopes established.
Conclusions:
- Compact high flux neutron generators are a viable tool for producing medical radioisotopes.
- The D-7Li reaction presents a promising pathway for efficient radioisotope generation.
- Advancements in neutron generator technology facilitate medical applications.
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