Related Experiment Video
Updated: Feb 13, 2026

An Ex Vivo Tissue Culture Model of Cartilage Remodeling in Bovine Knee Explants
Published on: November 3, 2019
Knee Cartilage Repair and Restoration: Common Problems and Solutions
Kristina Linnea Welton1, Stephanie Logterman2, Justin H Bartley1
1Department of Orthopedic Surgery - Sports Medicine, University of Colorado, CU Sports Medicine and Performance Center, 2150 Stadium Drive, Boulder, CO 80309, USA.
Abstract:
Focal cartilage defects in the knee are commonly found on MRI and arthroscopically. When these lesions are symptomatic and fail nonoperative management several surgical strategies are available. Common surgical techniques include reparative (ie, microfracture) and restorative procedures (ie, autologous chondrocyte implantation, particulated juvenile allograft cartilage, osteochondral autograft transfer, and osteochondral allograft). Each of these surgical procedures have shared and novel complications associated with their use. This article provides a detailed, case-based discussion of common complications encountered in surgical procedures for focal cartilage defects of the knee, highlighting causes, clinical recognition, and how to address and avoid these complications.
Related Concept Videos
Overview of DNA Repair
Chemically...
Restorative Care
Common Ion Effect
Base Excision Repair
The first step of...
Mismatch Repair
Knee Joint
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...

