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Left Ventricular Assist Devices - A State of the Art Review
Christina Feldmann1, Anamika Chatterjee1, Axel Haverich1
1Department of Cardiac-, Thoracic-, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Insights
Ventricular assist devices offer a vital solution for end-stage heart failure, addressing donor shortages and long transplant wait times. This review covers current left ventricular assist devices (LVADs), designs, implantation, and associated challenges.
Area of Science:
- Cardiology
- Biomedical Engineering
- Medical Technology
Background:
- Cardiovascular diseases are a primary global cause of mortality.
- Shortage of heart donors and long waiting lists impact transplant accessibility.
- Ventricular assist devices (VADs) are crucial for end-stage heart failure management.
Purpose of the Study:
- To review current implantable left ventricular assist devices (LVADs).
- To discuss various LVAD design concepts and implantation techniques.
- To highlight challenges associated with LVAD implantation, including infections and thromboembolic events.
Main Methods:
- Literature review of current implantable left ventricular assist devices.
- Analysis of different LVAD design concepts.
- Examination of implantation techniques and associated complications.
Main Results:
- Overview of available LVAD technologies.
- Discussion of diverse design approaches and surgical implantation methods.
- Identification of key challenges like infection and thromboembolism.
Conclusions:
- LVADs are increasingly important in treating end-stage heart failure.
- Understanding designs, implantation, and risks is crucial for effective therapy.
- Further research and technological advancements are needed to mitigate LVAD complications.
Abstract:
Cardiovascular diseases are the leading cause of mortality rates throughout the world. Next to an insufficient number of healthy donors, this has led to increasing numbers of patients on heart transplant waiting lists with prolonged waiting times. Innovative technological advancements have led to the production of ventricular assist devices that play an increasingly important role in end stage heart failure therapy. This review is intended to provide an overview of current implantable left ventricular assist devices, different design concepts and implantation techniques. Challenges such as infections and thromboembolic events that may occur during LVAD implantations have also been discussed.
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