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Updated: Feb 13, 2026

Murine Model of Wound Healing
Published on: May 28, 2013
The Effect of a Hydrocolloid Dressing on Second Intention Wound Healing in Cats
Vassiliki Tsioli1, Pagona G Gouletsou1, Apostolos D Galatos1
1From the Department of Surgery (V.T., A.D.G., A.L., A.I.S.) and Department of Obstetrics and Reproduction (P.G.G.), Faculty of Veterinary Medicine, University of Thessaly, Karditsa, Greece; and the Department of Clinical Studies, Companion Animal Clinic (L.G.P.), and Laboratory of Pathology (D.P.), School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Abstract:
The objective of the present study was to evaluate the effect of a hydrocolloid dressing on second intention wound healing in cats. Two full-thickness skin wounds, measuring 2 × 2 cm, were created on both sides of the dorsal midline of 10 cats; bilaterally, one randomly selected wound was bandaged with a hydrocolloid dressing and the second one (control) with a semiocclusive pad. Subjective clinical evaluation of granulation tissue formation, of the quantity and nature of wound exudate, and planimetry were performed on the right-side wounds, and histological examination on the left. No significant differences in subjective clinical evaluation or in planimetry were observed between the hydrocolloid-treated wounds and controls. Most wounds had serous or absence of exudate (41.25% and 25%, respectively), whereas purulent exudate was observed in 7.5% of wounds. Edema was significantly increased in the hydrocolloid-treated wounds compared with controls on day 7 but no significant differences in the other histological variables were observed.
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