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Updated: Feb 12, 2026

Isolation of Pulmonary Artery Smooth Muscle Cells from Neonatal Mice
Published on: October 19, 2013
Giant Pulmonary Hamartoma with Dominant CD34- Positive Smooth Muscle Cell Component
Masashi Miyaoka1, Go Ogura, Rurika Hamanaka
1Department of Pathology, Tokai University School of Medicine,143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan. mm946645@tsc.u-tokai.ac.jp.
Abstract:
Pulmonary hamartoma (PH) is usually a solid mass of less than 4 cm in size that contains cartilage omponents. A 44-year-old Japanese woman received surgical resection of a well-demarcated cystic tumor in the right lung. Resected tissue contained a 13 × 10 × 8 cm-sized solid mass with a prominent unilocular cyst (8 × 6.5 × 5 cm). The tumor was composed of a dominant smooth muscle cell (SMC) component with entrapped glandular respiratory epithelium. There was little cartilaginous or fatty tissue. Immunohistochemically, SMC was positive for smooth muscle actin (SMA) and desmin, as well as CD34. We report a unique case of giant pulmonary hamartoma with a dominant CD34 (+) SMC component.
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