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Plasma Polishing as a New Polishing Option to Reduce the Surface Roughness of Porous Titanium Alloy for 3D Printing
Published on: April 28, 2023
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Osteoconductivity of Binary Titanium Alloys with Different Micro/Nanoporous Surfaces
Journal of Nanoscience and Nanotechnology
|April 19, 2018
Summary
Micro-arc oxidation and hydrothermal treatment enhanced titanium alloy osteoconductivity. Ti–5Mn, Ti–5Nb, and Ti–5Pd alloys showed improved cellular activity, unlike Ti–5Au, highlighting surface morphology
Area of Science:
- Biomaterials Science
- Surface Engineering
- Orthopedic Research
Background:
- Titanium (Ti) alloys are crucial for orthopedic implants due to their biocompatibility.
- Surface modification techniques like micro-arc oxidation (MAO) and hydrothermal treatment (HT) aim to improve implant osseointegration.
- Understanding the relationship between surface characteristics and osteoconductivity is vital for developing advanced implant materials.
Purpose of the Study:
- To evaluate the surface characteristics and osteoconductivity of micro/nanoporous titanium alloys.
- To investigate the effects of MAO and HT on binary Ti-5 wt% A alloys (A = Au, Mn, Nb, Pd).
- To correlate surface morphology with cellular responses, including protein, ALPase, and osteocalcin production.
Main Methods:
- Preparation of binary Ti-5 wt% A alloys (A = Au, Mn, Nb, Pd) using MAO and HT.
- Surface characterization via X-ray diffractometry, scanning electron microscopy, and energy dispersive X-ray spectroscopy.
- Osteoconductivity assessment by quantifying total protein, alkaline phosphatase (ALPase) activity, and osteocalcin production in MG-63 cells.
Main Results:
- Surface morphology significantly influenced osteoconductivity.
- MAO/HT-treated Ti–5Mn, Ti–5Nb, and Ti–5Pd alloys exhibited enhanced ALPase activity and osteocalcin production compared to commercially pure Ti (cp-Ti).
- Ti–5Mn (MAO/HT) showed a notable increase in ALPase activity due to its well-developed micro/nano structure, while Ti–5Au (MAO/HT) displayed reduced cellular activity.
Conclusions:
- Micro/nanoporous surface structures created by MAO and HT can significantly enhance the osteoconductivity of titanium alloys.
- Ti–5Mn, Ti–5Nb, and Ti–5Pd alloys demonstrate promising potential for orthopedic applications due to improved cellular responses.
- Surface morphology, particularly the presence of nanorods, critically impacts the biological performance of modified titanium surfaces.
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