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Multiple RPAs make WRN syndrome protein a superhelicase

Mina Lee1, Soochul Shin2, Heesoo Uhm2

  • 1Center for Nano-Bio Measurement, Korea Research Institute of Standards and Science, Daejeon, Republic of Korea.

Nucleic Acids Research
|April 19, 2018
PubMed
Summary

Replication protein A (RPA) transforms the Werner syndrome protein (WRN) from a weak DNA helicase into a superhelicase. Multiple RPA binding dramatically enhances WRN

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