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Silver nanoparticles-embedded nanopaper as a colorimetric chiral sensing platform.
1Department of Science Education, A. K. Education Faculty, Necmettin Erbakan University, Konya 42090, Turkey.
Talanta
|April 21, 2018
Summary
This study introduces a novel optical sensor using silver nanoparticles embedded in bacterial cellulose nanopaper for detecting chiral molecules like D-cysteine. This simple, inexpensive sensor offers a new method for enantioselective analysis in various applications.
Area of Science:
- Nanomaterials Science
- Analytical Chemistry
- Biomaterials Engineering
Background:
- Paper-based sensors offer simple, rapid, and inexpensive analytical devices for medical, food, and environmental applications.
- Enantioselective recognition of chiral analytes is crucial in various scientific fields.
- Existing methods for chiral analysis can be complex and costly.
Purpose of the Study:
- To develop a new optical sensing platform for enantioselective recognition of chiral analytes.
- To utilize in-situ synthesized silver nanoparticles (AgNPs) embedded within transparent nanopaper.
- To create a simple, disposable device for practical chiral analysis.
Main Methods:
- Nanopaper was fabricated using an eco-friendly approach with bacterial cellulose nanofibers.
- Silver nanoparticles were embedded into the nanopaper via an in-situ generation method.
- The chiral recognition capability of AgNPs was tested in both solution and nanopaper formats.
Main Results:
- The AgNPs demonstrated enantioselective sensing towards D-cysteine with a limit of detection (LOD) of 4.88 µM.
- Chiral recognition is based on the aggregation of AgNPs upon interaction with enantiomers, causing a visible color change (yellow to purple-brown).
- Disposable, two-dimensional cuvettes were fabricated from the plasmonic nanopaper for use in standard spectrophotometers.
Conclusions:
- The developed nanopaper-based sensor provides an effective platform for enantioselective optical sensing.
- The fabricated disposable cuvettes enable the successful determination of enantiomeric percentages, demonstrated with D-cysteine.
- This technology holds promise for simple, rapid, and cost-effective chiral analysis in diverse fields.
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