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Updated: Feb 11, 2026

Hydrogen Production and Utilization in a Membrane Reactor
Published on: March 10, 2023
Asymmetric transfer hydrogenation reactions of N-sulfonylimines by using alcohols as hydrogen sources
Fan Yang1, Jingchao Chen, Guoli Shen
1YMU-HKBU Joint Laboratory of Traditional Natural Medicine, Yunnan Minzu University, Kunming, 650500, China. chenjingchao84@163.com adams.bmf@hotmail.com.
Abstract:
A palladium/zinc co-catalytic system was established and successfully utilized in the asymmetric transfer hydrogenation reactions of N-sulfonylimines with alcohols as hydrogen sources. Simple alcohols such as methanol, ethanol and benzyl alcohols are all variable hydrogen sources that can reduce various N-sulfonylimines to the corresponding chiral amines with high optical purities in presence of this co-catalytic system. Primary mechanistic study revealed that the reaction may initiate with a Pd-hydride intermediate.
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