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Adult Intestinal Transplantation

Cal S Matsumoto1, Sukanya Subramanian1, Thomas M Fishbein1

  • 1Medstar Georgetown University Hospital, Medstar Georgetown Transplant Institute, 3800 Reservoir Road, Northwest, 2 PHC Building, Washington, DC 20007, USA.

Gastroenterology Clinics of North America
|May 9, 2018
PubMed

Adult intestinal transplantation differs significantly from pediatric intestinal transplantation. While indications have remained largely consistent since 2000, indications for adults have expanded over the last two decades to include motility disorders and desmoid tumors. Graft type in adult recipients depends on the distinct anatomic characteristics of the adult recipient. Colonic inclusion, while initially speculated to portend unfavorable outcomes due to complex host-bacterial interactions has increased over the past two decades with superior graft survival and improved patient quality of life. Overall, outcomes have steadily improved. For adult intestinal transplant candidates, intestinal transplantation remains a mainstay therapy for complicated intestinal failure and is a promising option for other life threatening and debilitating conditions.

Keywords:
Adult intestinal transplantationIntestinal transplant indicationsIntestinal transplant outcomeVirtual crossmatch

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