Huge Candida albicans normal native tricuspid valve endocarditis

Area of Science:

• Infectious Diseases
• Cardiology
• Mycology

Background:

• Fungal endocarditis, particularly Candida spp., is a rare but significant complication in modern medicine.
• Medical advancements and lifestyle factors contribute to the rise of such infections.

Observation:

• A case of a young, bedridden quadriplegic woman with recurrent pneumonia treated with antibiotics.
• Autopsy revealed severe Candida native valve infective endocarditis (CIE).

Findings:

• Prolonged antibiotic therapy was identified as a potential risk factor for CIE development.
• Immobility and central venous catheter use were considered additional contributing factors.
• Absence of peripheral embolization was noted in this right-sided heart endocarditis case.

Implications:

• Highlights the importance of considering fungal endocarditis in susceptible patients.
• Suggests careful monitoring and risk assessment in patients with prolonged antibiotic use and immobility.
• Informs clinical practice regarding potential complications in immunocompromised or critically ill patients.